{"type":"standard","title":"Phototrexate","displaytitle":"Phototrexate","namespace":{"id":0,"text":""},"wikibase_item":"Q63455837","titles":{"canonical":"Phototrexate","normalized":"Phototrexate","display":"Phototrexate"},"pageid":60678583,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/Cis-Phototrexate_skeletal.svg/330px-Cis-Phototrexate_skeletal.svg.png","width":320,"height":297},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/Cis-Phototrexate_skeletal.svg/444px-Cis-Phototrexate_skeletal.svg.png","width":444,"height":412},"lang":"en","dir":"ltr","revision":"1273816694","tid":"31d6ef89-e2b2-11ef-92ba-6ce02c2a785d","timestamp":"2025-02-04T04:40:44Z","description":"Photopharmacological agent","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Phototrexate","revisions":"https://en.wikipedia.org/wiki/Phototrexate?action=history","edit":"https://en.wikipedia.org/wiki/Phototrexate?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Phototrexate"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Phototrexate","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Phototrexate","edit":"https://en.m.wikipedia.org/wiki/Phototrexate?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Phototrexate"}},"extract":"Phototrexate is a photochromic antifolate drug developed at the Institute for Bioengineering of Catalonia. In particular, it is a photopharmacological agent that behaves as light-regulated inhibitor of the dihydrofolate reductase (DHFR) enzyme. Phototrexate is a photoisomerizable structural analogue of the chemotherapy agent methotrexate. It is also an example of \"azologization\". Pharmacological effects of phototrexate can be switched on and off by UVA and visible light, respectively. Phototrexate is almost inactive in its trans configuration while it behaves as a potent antifolate in its cis configuration. It can also spontaneously self-deactivate in the dark.","extract_html":"
Phototrexate is a photochromic antifolate drug developed at the Institute for Bioengineering of Catalonia. In particular, it is a photopharmacological agent that behaves as light-regulated inhibitor of the dihydrofolate reductase (DHFR) enzyme. Phototrexate is a photoisomerizable structural analogue of the chemotherapy agent methotrexate. It is also an example of \"azologization\". Pharmacological effects of phototrexate can be switched on and off by UVA and visible light, respectively. Phototrexate is almost inactive in its trans configuration while it behaves as a potent antifolate in its cis configuration. It can also spontaneously self-deactivate in the dark.
"}{"fact":"The most traveled cat is Hamlet, who escaped from his carrier while on a flight. He hid for seven weeks behind a panel on the airplane. By the time he was discovered, he had traveled nearly 373,000 miles (600,000 km).","length":217}
{"fact":"A cat has 230 bones in its body. A human has 206. A cat has no collarbone, so it can fit through any opening the size of its head.","length":130}
{"type":"standard","title":"Niuma","displaytitle":"Niuma","namespace":{"id":0,"text":""},"wikibase_item":"Q58411270","titles":{"canonical":"Niuma","normalized":"Niuma","display":"Niuma"},"pageid":58582170,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/en/6/66/Niuma_%28movie_poster%29.jpg","width":265,"height":374},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/en/6/66/Niuma_%28movie_poster%29.jpg","width":265,"height":374},"lang":"en","dir":"ltr","revision":"1260737618","tid":"f858ebbd-b094-11ef-aab2-5e205d092e08","timestamp":"2024-12-02T10:05:34Z","description":"2010 Maldivian drama film","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Niuma","revisions":"https://en.wikipedia.org/wiki/Niuma?action=history","edit":"https://en.wikipedia.org/wiki/Niuma?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Niuma"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Niuma","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Niuma","edit":"https://en.m.wikipedia.org/wiki/Niuma?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Niuma"}},"extract":"Niuma is a 2010 Maldivian drama film directed by Niuma Mohamed. Produced by Mohamed Abdulla under Dhekedheke Ves Production, the film stars Niuma Mohamed, Yoosuf Shafeeu, Ahmed Nimal, Mohamed Manik, and Sheela Najeeb in pivotal roles. The film was released on 25 October 2010. The entire production was shot in B. Goidhoo.","extract_html":"
Niuma is a 2010 Maldivian drama film directed by Niuma Mohamed. Produced by Mohamed Abdulla under Dhekedheke Ves Production, the film stars Niuma Mohamed, Yoosuf Shafeeu, Ahmed Nimal, Mohamed Manik, and Sheela Najeeb in pivotal roles. The film was released on 25 October 2010. The entire production was shot in B. Goidhoo.
"}{"slip": { "id": 184, "advice": "You can fail at what you don't want. So you might as well take a chance on doing what you love."}}
{"slip": { "id": 165, "advice": "Eliminate the unnecessary."}}
{"type":"standard","title":"Dolní Hbity","displaytitle":"Dolní Hbity","namespace":{"id":0,"text":""},"wikibase_item":"Q968366","titles":{"canonical":"Dolní_Hbity","normalized":"Dolní Hbity","display":"Dolní Hbity"},"pageid":23586285,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/02/Doln%C3%AD_Hbity_od_jihu.JPG/330px-Doln%C3%AD_Hbity_od_jihu.JPG","width":320,"height":240},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/0/02/Doln%C3%AD_Hbity_od_jihu.JPG","width":1000,"height":750},"lang":"en","dir":"ltr","revision":"1269570429","tid":"dc49b10c-d320-11ef-9705-4e8498704b93","timestamp":"2025-01-15T09:12:36Z","description":"Municipality in Central Bohemian, Czech Republic","description_source":"local","coordinates":{"lat":49.6575,"lon":14.17},"content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Doln%C3%AD_Hbity","revisions":"https://en.wikipedia.org/wiki/Doln%C3%AD_Hbity?action=history","edit":"https://en.wikipedia.org/wiki/Doln%C3%AD_Hbity?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Doln%C3%AD_Hbity"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Doln%C3%AD_Hbity","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Doln%C3%AD_Hbity","edit":"https://en.m.wikipedia.org/wiki/Doln%C3%AD_Hbity?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Doln%C3%AD_Hbity"}},"extract":"Dolní Hbity is a municipality and village in Příbram District in the Central Bohemian Region of the Czech Republic. It has about 900 inhabitants.","extract_html":"
Dolní Hbity is a municipality and village in Příbram District in the Central Bohemian Region of the Czech Republic. It has about 900 inhabitants.
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